Anti-Quadruplex DNA [5E11]

Catalogue Number: AB00392-24.1-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:G4 DNA
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Goat
Clone: 5E11
Isotype: IgG
Immunogen: Ver-3 or d(TGGGGG(TTAGGG)2T
Application: ELISA, IHC

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody binds to quadruplex DNA, which is generated through the association of four guanines bound through Hoogsteen base pairing. G4-forming sequences are associated with immunoglobulin switch regions, promoter sequences, rDNA and telomeric repeats.

Short Description

This chimeric goat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.