Anti-Glucose-dependent insulinotropic Receptor [Gipg013]
Catalogue Number: AB00424-201.1-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | GIPR |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Dog |
| Clone: | Gipg013 |
| Isotype: | IgG2 |
| Immunogen: | Human GIPr. |
| Application: | ELISA, IF, Blk |
Additional Text
Gene ID
139760
Gene Name
GPR119
Uniprot ID
Q8TDV5
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody binds to GIPr, a GPCR expressed on pancreatic beta-cells, where activation leads to the release of insulin. Endogeonous ligands for the receptor include oleylethanolamide and lysophosphatidylcholine. The antibody acts as a competitive antagonist. In rat islets, the antibody inhibits GIP-induced secretion of insulin by up to 81%.
Short Description
This chimeric dog antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
AB00424-201.1-BT Datasheet
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