Anti-EGFR [L3 11D]
Catalogue Number: AB00455-23.0-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Epidermal growth factor receptor; ERBB; ERBB1; HER1; mENA; PIG61; NISBD2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Rabbit |
| Clone: | L3 11D |
| Isotype: | IgG |
| Immunogen: | Human EGFR. |
| Application: | ELISA, FC, SDS-PAGE, WB |
Additional Text
Gene ID
1956
Gene Name
EGFR
Uniprot ID
P00533
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
The antibody binds specifically to EGFR, a cell-surface receptor which is part of the ErbB family of receptors. The EGFR is a receptor tyrosine kinase, which, upon activation by its ligands, such as epidermal growth factor and transforming growth factor alpha, triggers signal transduction pathways that increase cell migration, adhesion and proliferation. Mutations that lead to the overexpression of EGFR are associated with the development of cancer. The antibody was prepared from phage antibodies isolated from the lymph node library.
Short Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv antibody fragment format, for improved compatibility with existing reagents, assays and techniques.
AB00455-23.0 Datasheet
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