Anti-Complement Factor I [OX-21]
Catalogue Number: AB00565-10.3-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | C3b/C4b inactivator; CFI; AHUS3; ARMD13; C3BINA; C3b-INA; FI; IF; KAF |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Human |
| Clone: | OX-21 |
| Isotype: | IgG1 |
| Immunogen: | C3bINA was purified from outdated human plasma, and subcutaneously injected into DBA/2 x Balb/c F1 mice. |
| Application: | ELISA, FC, IHC-P, IP, WB, RIA, IHC |
Additional Text
Uniprot ID
P05156
Gene ID
3426
Gene Name
CFI
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody binds C3bINA, and consequently can be used to rapidly purify enzymically-active C3bINA from human plasma using affinity chromatography (Hsiung, 1982), permitting the molecular characterisation of C3bINA. This technique has a variety of benefits, as it allows the purification of serum proteins at low concentration and the extraction of high yields and active enzymes, as well as being time-efficient.
Short Description
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB00565-10.3-BT Datasheet
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