Anti-CD172b / SIRPB [OX-130]

Catalogue Number: AB00572-10.0-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:SIRP-beta-1; Signal-regulatory protein beta-1; CD172 antigen-like family member B
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Human
Clone: OX-130
Isotype: IgG1
Immunogen: Recombinant SIRPβ1 was purified by nickel affinity chromatography and used to immunize mice.
Application: ELISA, FC, SPR

Additional Text

Gene Name

SIRPB1

Gene ID

10326

Uniprot ID

O00241

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody binds both common alleles of the human activating SIRPβ1 receptor, but ELISA and surface plasmon resonance results have shown that it reacts with one of the two common alleles of SIRPα, potentially yielding different outcomes when this antibody is used in assays from different individuals.

Short Description

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.