Anti-CD11a/CD18 [YKIX490.6.4]
Catalogue Number: AB00593-201.4-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | αLβ2 integrin; integrin alpha-L; integrin beta-2; LeuCAM |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Dog |
| Clone: | YKIX490.6.4 |
| Isotype: | IgG2 |
| Immunogen: | This antibody was prepared by immunizing rats with canine thymocytes |
| Application: | FC, IHC-P, IP, IHC-Fr, IHC-R, Blk |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody binds CD11a/18, and has been shown to block T cell proliferation, cytotoxic T lymphocyte (CTL) lysis, antibody dependent cell mediated cytotoxic (ADCC) lysis and homotypic cell adhesion (Cobbold, 1994). This antibody has been used in IF and IP analysis to identify and characterise the canine homologue of human CD11a/18.
Short Description
This chimeric dog antibody was made using the variable domain sequences of the original Rat IgG2c format, for improved compatibility with existing reagents, assays and techniques.
AB00593-201.4 Datasheet
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