Anti-CD11a/CD18 [YKIX490.6.4]

Catalogue Number: AB00593-23.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:αLβ2 integrin; integrin alpha-L; integrin beta-2; LeuCAM
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Rabbit
Clone: YKIX490.6.4
Isotype: IgG
Immunogen: This antibody was prepared by immunizing rats with canine thymocytes
Application: FC, IHC-P, IP, IHC-Fr, IHC-R, Blk

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody binds CD11a/18, and has been shown to block T cell proliferation, cytotoxic T lymphocyte (CTL) lysis, antibody dependent cell mediated cytotoxic (ADCC) lysis and homotypic cell adhesion (Cobbold, 1994). This antibody has been used in IF and IP analysis to identify and characterise the canine homologue of human CD11a/18.

Short Description

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat lgG2c format, for improved compatibility with existing reagents, assays and techniques.