Anti-Fibronectin [A2]

Catalogue Number: AB00634-10.6-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:FN; EDB(+) FN; ED-B domain of fibronectin; Extra domain-B containing fibronectin
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Human
Clone: A2
Isotype:
Immunogen: 2D-PAGE gel isolated human Extra-Domain containing fibronectin from lysate of human melanoma COLO-38 cells.
Application: ELISA, WB, IHC-Fr, SPR

Additional Text

Gene Name

FN1

Gene ID

2335

Uniprot ID

P02751

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Extra domain-B containing fibronectin has been proposed marker of angiogenesis, has been shown to be expressed in a number of human cancers and in ocular neovascularization in patients with proliferative diabetic retinopathy.

Short Description

This reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.