Anti-Fibronectin [G4]

Catalogue Number: AB00635-10.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:EDB(+) FN; ED-B domain of fibronectin;Extra domain-B containing fibronectin
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Human
Clone: G4
Isotype: IgG1
Immunogen: 2D-PAGE gel isolated human Extra-Domain containing fibronectin from lysate of human melanoma COLO-38 cells.
Application: ELISA, WB, IHC-Fr, SPR

Additional Text

Gene Name

FN1

Gene ID

2335

Uniprot ID

P02751

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Extra domain-B containing fibronectin has been proposed marker of angiogenesis, has been shown to be expressed in a number of human cancers and in ocular neovascularization in patients with proliferative diabetic retinopathy.

Short Description

This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.