Anti-CD3 epsilon [12F6]
Catalogue Number: AB00640-23.0-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Leu4/T3; ET-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Rabbit |
| Clone: | 12F6 |
| Isotype: | IgG |
| Immunogen: | Human CD3 |
| Application: | FC, Act |
Additional Text
Gene Name
CD3E
Gene ID
916
Uniprot ID
P07766
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody competes for CD3 binding with the therapeutic antibody OKT3 (Ab00122). 12F6 binding to CD3 on human T-cells stimulates the secretion of TNF-alpha, INF-gamma and IL-10. Humanized versions of this antibody are also available.
Short Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
AB00640-23.0 Datasheet
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