Anti-CD81 [1D6]
Catalogue Number: AB00697-10.3-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Tetraspanin-28; TAPA-1; Target of the Antiproliferative Antibody 1; Tspan-28 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Human |
| Clone: | 1D6 |
| Isotype: | IgG1 |
| Immunogen: | This antibody was produced by immunizing mice with 5A6-aggregated OCI-LY8 B cells. |
| Application: | ELISA, FC, ICC, IF, IHC-P, IP, WB, FA |
Additional Text
Gene Name
CD81
Gene ID
975
Uniprot ID
P60033
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody is a strong inducer of homotypic adhesion in hematolymphoid cells (Levy, 1998). This antibody also has an anti-proliferative effect, and is able to induce growth inhibition of B cell lines. Triggering of CD81 by this antibody induces a significant upregulation of the constituitive release of TNF-α by JY cells, an Eptsein-Barr virus-positive B lymphoblastoid cell line (Altomonte, 1995).
Short Description
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB00697-10.3 Datasheet
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