Anti-IgE [huMaE11 (Omalizumab)]

Catalogue Number: AB00717-23.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Monoclonal Secondary Antibody - Unconjugated
Alias:epsilon chain; Ig epsilon chain C region; immunoglobulin E
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Rabbit
Clone: huMaE11 (Omalizumab)
Isotype: IgG
Immunogen: Human IgE protein.
Application: ELISA, Blk, Crstion

Additional Text

Uniprot ID

P01854

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Short Description

NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Application Notes

This antibody is the humanized version of original mouse antibody MAE11. This antibody binds to circulating IgE, thereby inhibiting IgE binding to mast-cells. It does not bind to cell-bound IgE and does not provoke histamine release from mast-cells sensitised by IgE. As a human IgG1, marketed as Xolair™, it is used therapeutically to treat asthma and allergies.