Anti-Thrombopoietin [TN1 ]
Catalogue Number: AB00746-1.1-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | C-mpl ligand; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; TPO |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Mouse |
| Clone: | TN1 |
| Isotype: | IgG1 |
| Immunogen: | TN1 was prepared by immunizing BALB/c mice by intraperitoneal injecction of recombinant human TPO. The Fab fragment was produced via incubation with papain which cleaves at the hinge region of the IgG to remove the Fc region. The product is then subsequently incubated under reducing conditions and the free Cys residue blocked with iodoacetamide. |
| Application: | ELISA, NT, Crstion |
Additional Text
Gene ID
7066
Gene Name
THPO
Uniprot ID
P40225
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
TN1 can neutralize the biological activity of TPO and can be used to detect TPO in ELISA studies. The Fab fragement of TN1 can also be used to aid the crystallisation of TPO by increasing the area upon which stable crystal contacts can be made (PMID: 11976502).
AB00746-1.1-BT Datasheet
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