Anti-RRV E2 [D7]
Catalogue Number: AB00749-23.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | RRV Envelope gp; Ross River Virus envelope glycoprotein; O'nyong-nyong VLP; Chikungunya VLP; CHIKV-VLP |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Rabbit |
| Clone: | D7 |
| Isotype: | IgG |
| Immunogen: | This antibody was raised by immunizing mice. |
| Application: | ELISA, FC, Lbl |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
UniProt ID
Q88724
Application Notes
This antibody binds RRV E2, and has been used to stain RRV-positive cells and in FC analysis of E2 surface expression (Jupille, 2013). This antibody has also been used to detect RRV binding to HeLa cells, demonstrating that synthetic peptides representing the α1β1 integrin binding site on collagen IV are able to inhibit RRV binding to cells, thus implicating the α1β1 integrin as an RRV cell-binding receptor (La Linn, 2005). This antibody can be used for the detection of Ross river virus E2 protein, O'nyong-nyong VLP (ONNV VLP) and Chikungunya VLP (CHIKV-VLP) in an ELISA.
Short Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.
AB00749-23.0-BT Datasheet
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