Anti-Glycoprotein H [A13-d6.3]

Catalogue Number: AB00772-3.3-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:d6.3; gH; Envelope glycoprotein H
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Mouse
Clone: A13-d6.3
Isotype: IgG2b
Immunogen: d6.3 was generated by immunizing mice with PrV.
Application: NT, IS, Crstion

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Uniprot ID

A0A142I9U7

Application Notes

d6.3 neutralizes the ΔgL-Pass PrV variant of PrV and can stain ΔgL-Pass PrV variant but not the wild-type PrV by immunostaining. The epitope of d6.3 is not blocked by the formation of the gH/gL heterodimer. The d6.3Fab fragment (obtained through papain digestion) can be complexed with the core fragment of the PrV glycoprotein H (gH) ectodomain (aa 107-639) for structural studies by crystallography.