Catalogue Number: AB00813-2.3-VCS-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | CD279; PD1; PDCD1; RMPI-14; RMP1/14; Programmed Death Receptor 1; Programmed Death 1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 2 x 1 mg |
| Host name: | Mouse |
| Clone: | RMP1-14 |
| Isotype: | IgG2a |
| Immunogen: | The original rat hybridoma was generated by immunizing Sprague Dawley rats with mouse PD-1-transfectked BHK cells. A P3U1 myeloma was used as the fusion partner. |
| Application: | FC, IHC-Fr, Blk |
Recombinant Monoclonal
All VivopureX products are formulated in PBS only without addition of preservatives. To ensure optimal storage and prevent microbial contamination, only open and dispense under sterile conditions. Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Binding of the original rat IgG2a antibody to PD1 has been reported to prevent binding of both B7-H1-Ig (PD-L1-Ig) and B7-DC-Ig (PD-L2-Ig) fusion proteins to PD1.
This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.