Anti-CD70 [BU69]
Catalogue Number: AB00818-23.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | TNFRS7; Tumor Necrosis Factor Ligand Superfamily Member 7; CD27 Ligand; CD27LG; TNFSF7; CD27L; Tumor Necrosis Factor Ligand 8A; Surface Antigen CD70; Ki-24 Antigen; CD70 Antigen; TNLG8A; TAN1-7; TAN17 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Rabbit |
| Clone: | BU69 |
| Isotype: | IgG |
| Immunogen: | Murine antibodies were produced by immunising BALB/c mice using the Waldenstrom's macroglobulinaemia cell line WM-1. Hybridomas were generated by fusion of immunised cells with the myeloma cell line P3/NS1/1-Ag4.1 via established methods. |
| Application: | FACS, FC, IP, IHC |
Additional Text
Gene Name
CD70
Gene ID
970
Uniprot ID
P32970
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
BU69 has been used for FACS and immunocytochemistry analysis of the cell-surface expression levels of CD70 in renal cell carcinomas (Adam et al, 2006). It was shown in this study that cell-surface binding of BU69 to CD70 caused rapid internalisation of the cell-surface glycoprotein.
Short Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB00818-23.0-BT Datasheet
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