Anti-CD72 [BU40]
Catalogue Number: AB00831-2.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Lyb-2; B-cell differentiation antigen CD72 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Mouse |
| Clone: | BU40 |
| Isotype: | IgG2a |
| Immunogen: | This antibody was raised against the HF B1 plasmacytoid cell line, which is considered to be late B-like. |
| Application: | FC, Act, Stim |
Additional Text
Gene Name
CD72
Gene ID
971
Uniprot ID
P21854
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody has been used to investigate cell-surface expression of CD72 in FACS analysis (Kataoka et al, 2013). This antibody has been shown to induce resting B cells to enter the G1 phase of the cell cycle, stimulate B cell expression of major histocompatibility complex class II antigen and potentiate the capacity of IL-4 to induce CD23 production (Katira et al, 1992). It also stimulates TNF-α and IL-6 production in CD14+ monocytes (Yoshida et al, 2015). Ligation of CD72 by this antibody has been observed to suppress the proliferation of an acute myelogenous leukaemia cell line (Kataoka et al, 2013).
AB00831-2.0-BT Datasheet
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