Anti-V(beta)3 TCR [JOVI.1]
Catalogue Number: AB00846-2.3-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Mouse |
| Clone: | JOVI.1 |
| Isotype: | IgG2a |
| Immunogen: | Thymus, spleen and mesenteric lymph nodes isolated from a mouse transgenic for human Vb3 TcR. |
| Application: | FACS, FC, IF, IP, IHC |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody can be used to detect the TCR beta chain in a majority (50-75%) of T-cell receptors by flow cytometry, immunofluorescence and can immunoprecipitate the TCR beta protein (variant 1). Recently it has been combined into a chimeric antigen antigen receptor therapy approach to selectively deplete a subset of T-cells in T-cell lymphomas or leukaemias, whilst leaving the non-reactive T-cell subset intact.
AB00846-2.3 Datasheet
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