Anti-Factor VIII:c light chain [RFF-VIII:c/5]

Catalogue Number: AB00848-1.1-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:AHF; Antihemophilic factor; coagulation factor VIII; procoagulant component; coagulation factor VIIIc; DXS1253E; F8Ccoagulation factor VIII; factor VIII F8B; FVIII; HEMAF8B; Procoagulant component
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Mouse
Clone: RFF-VIII:c/5
Isotype: IgG1
Immunogen: This antibody was raised by immunising BALB/C mice with highly purified procoagulant factor VIII (VIII: C)
Application: IRMA, Blk

Additional Text

Gene Name

F8

Uniprot ID

P00451

Gene ID

2157

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody is a coagulation inhibitor, though displays only weak anticoagulant activity (Rotblat et al, 1983). It has been used as the solid-phase immunoadsorbent in a two-site immunoradiometric assay of Factor VIII:c (Rotblat et al, 1983).When bound to Sepharose columns, this antibody has been used to deplete factor VII:c from plasma through column chromatography (Takase et al, 1987).