Anti-Factor VIII:c light chain [RFF-VIII:c/5]

Catalogue Number: AB00848-10.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:AHF; Antihemophilic factor; coagulation factor VIII; procoagulant component; coagulation factor VIIIc; DXS1253E; F8Ccoagulation factor VIII; factor VIII F8B; FVIII; HEMAF8B; Procoagulant component
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Human
Clone: RFF-VIII:c/5
Isotype: IgG1
Immunogen: This antibody was raised by immunising BALB/C mice with highly purified procoagulant factor VIII (VIII: C)
Application: IRMA, Blk

Additional Text

Gene Name

F8

Uniprot ID

P00451

Gene ID

2157

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody is a coagulation inhibitor, though displays only weak anticoagulant activity (Rotblat et al, 1983). It has been used as the solid-phase immunoadsorbent in a two-site immunoradiometric assay of Factor VIII:c (Rotblat et al, 1983).When bound to Sepharose columns, this antibody has been used to deplete factor VII:c from plasma through column chromatography (Takase et al, 1987).

Short Description

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.