Anti-NMDA Receptor [17]

Catalogue Number: AB00900-8.1-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:NMDAR; NMDA-R; Glutamate receptor
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Rat
Clone: 17
Isotype: IgG2b
Immunogen: Monoclonal antibodies that bind rat GluN2B ATD were obtained by immunizing mice with the purified intact GluN1-GluN2B NMDA receptors. IgGs were purified from hybridoma cell culture supernatant by Protein-A Sepharose. Fab fragments have been prepared by papain proteolysis followed by re-chromatographing onto Protein-A Sepharose to remove Fc.
Application: Crstapy

Additional Text

Gene Name

GRIN2B

Gene ID

24410

Uniprot ID

Q00960

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody has been used for the crystallisation of the NMDA receptor in the absence of an allosteric inhibitor at 2.9A (Tajima 2016).

Short Description

This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.