Anti-ectodysplasin A [EctoD2]
Catalogue Number: AB00912-1.1-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | O54693; Q92838; Ectodysplasin-A; EDA |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 1 mg |
| Host name: | Mouse |
| Clone: | EctoD2 |
| Isotype: | IgG1 |
| Immunogen: | This antibody was raised by immunising Eda-deficient Tabby mice with an active recombinant form of EDA1 (Fc-EDA1). |
| Application: | ELISA, FC, SDS-PAGE, WB, Blk |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
The specificity of this antibody for EDA has been confirmed in SDS-PAGE, Western blot, ELISA, native gel electrophoresis and FC experiments (Kowalczyk-Quintas et al, 2014). This antibody blocks mammalian and avian EDA1 and EDA2 from binding EDAR (Kowalczyk-Quintas et al, 2014). When administered to pregnant wild-type mice, this antibody induces foetal ectodermal dysplasia (Kowalczyk-Quintas et al, 2014). Therapeutically, this antibody may be useful in the treatment of disorders arising as a result of excessive EDA1 action.
AB00912-1.1-BT Datasheet
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