Anti-VSIG4 [Nb119]
Catalogue Number: AB00929-34.11-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Z39Ig; V-set and immunoglobulin domain-containing protein 4; Complement receptor of the Ig superfamily; CRIg; Protein Z39Ig; Z39Ig; Vsig4 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ug |
| Host name: | Camelid |
| Clone: | Nb119 |
| Isotype: | |
| Immunogen: | The extracellular domain of recombinantly-produced mouse VSIG4 was used to immunise an alpaca (Vicugna pacos). Peripheral blood lymphocytes isolated from the immunised alpaca were used to generate a Nanobody phage library, clones from which were selected for binding to the same recombinant mouse VSIG4 extracellular domain. |
| Application: | FC, WB, SPR, Crstion |
Additional Text
Gene ID
11326
Gene Name
VSIG4
Uniprot ID
Q9Y279
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
Nb119 was shown to exhibit an affinity for murine VSIG4 of 0.9 nM by SPR (Zheng et al, 2014) or 3.5 nM by ITC (Wen et al, 2017). It was further shown by flow cytometry that Nb119 recognised mouse VSIG4 expressed on liver macrophages. Nb119 was crystallised in complex with both murine and human VSIG4 (Wen et al, 2017).
AB00929-34.11-BT Datasheet
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