Anti-Parvovirus [MAbE]
Catalogue Number: AB00935-205.1-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | canine parvovirus; CPV; feline panleukopenia virus; FPV |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Dog |
| Clone: | MAbE |
| Isotype: | IgM |
| Immunogen: | This antibody was raised by immunising rats with feline panleukopenia virus (FPV)-b. |
| Application: | ELISA, IP, EM, RIA, NT |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody is able to neutralise FPV-a and -b and CPV- and -b in haemagglutination inhibition assays (Parrish & Carmichael, 1983). It has also been used in immunoprecipitation and RIA analysis (Parrish & Carmichael, 1983). A Fab derived from this antibody has also been shown, in ELISA experiments, to recognise CPV and FPV capsids (Nelson et al, 2007), and to potently neutralise CPV (Organtini et al, 2016). This Fab has also been used in cryo-electron microscopy to determine the structure of CPV (Organtini et al, 2016).
Short Description
This chimeric dog antibody was made using the variable domain sequences of the original Rat IgG2b format for improved compatibility with existing reagents assays and techniques.
AB00935-205.1 Datasheet
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