Catalogue Number: AB00935-205.1-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | canine parvovirus; CPV; feline panleukopenia virus; FPV |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ug |
| Host name: | Dog |
| Clone: | MAbE |
| Isotype: | IgM |
| Immunogen: | This antibody was raised by immunising rats with feline panleukopenia virus (FPV)-b. |
| Application: | ELISA, IP, EM, RIA, NT |
Purified
Recombinant Monoclonal
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
This antibody is able to neutralise FPV-a and -b and CPV- and -b in haemagglutination inhibition assays (Parrish & Carmichael, 1983). It has also been used in immunoprecipitation and RIA analysis (Parrish & Carmichael, 1983). A Fab derived from this antibody has also been shown, in ELISA experiments, to recognise CPV and FPV capsids (Nelson et al, 2007), and to potently neutralise CPV (Organtini et al, 2016). This Fab has also been used in cryo-electron microscopy to determine the structure of CPV (Organtini et al, 2016).
This chimeric dog antibody was made using the variable domain sequences of the original Rat IgG2b format for improved compatibility with existing reagents assays and techniques.