Anti-Envelope protein (soluble) [Z3L1]

Catalogue Number: AB00940-10.3-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:ZIKV sE; Zika virus soluble envelope protein; Zika virus envelope protein; ZIKV soluble envelope protein; ZIKV envelope protein; Zika virus sE protein; ZIKV sE protein; Z3-L1
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Human
Clone: Z3L1
Isotype: IgG1
Immunogen: Anti-ZIKV mAbs were obtained from the sera and peripheral blood mononuclear cells of a ZIKV-infected patient.
Application: ELISA, FC, NT, SPR, Crstion

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

Z3L1 was confirmed to bind ZIKV sE protein by ELISA, with an affinity of 5.39 uM shown by SPR (Wang et al, 2016). Using a FACS-based assay, it was shown that Z3L1 was sufficient for complete neutralisation of viral activity against infected C6/36 and Vero cells. In vivo, it has been shown that Z3L1 protected IFN receptor KO mice from ZIKV infection.