Anti-Envelope protein (soluble) [Z23]
Catalogue Number: AB00941-10.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | ZIKV sE; Zika virus soluble envelope protein; Zika virus envelope protein; ZIKV soluble envelope protein; ZIKV envelope protein; Zika virus sE protein; ZIKV sE protein; ZIKV sE; Z-23 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Human |
| Clone: | Z23 |
| Isotype: | IgG1 |
| Immunogen: | Anti-ZIKV mAbs were obtained from the sera and peripheral blood mononuclear cells of a ZIKV-infected patient. |
| Application: | ELISA, FC, NT, SPR |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
Z23 was confirmed to bind ZIKV sE protein by ELISA, with an affinity of 0.44 uM shown by SPR (Wang et al, 2016). Using a FACS-based assay, it was shown that Z23 potently neutralised viral activity against infected C6/36 and Vero cells. In vivo, Z23 completely protected IFN receptor KO mice from ZIKV infection.
AB00941-10.0-BT Datasheet
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