Anti-Envelope protein (soluble) [Z23]
Catalogue Number: AB00941-23.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | ZIKV sE; Zika virus soluble envelope protein; Zika virus envelope protein; ZIKV soluble envelope protein; ZIKV envelope protein; Zika virus sE protein; ZIKV sE protein; ZIKV sE; Z-23 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Rabbit |
| Clone: | Z23 |
| Isotype: | IgG |
| Immunogen: | Anti-ZIKV mAbs were obtained from the sera and peripheral blood mononuclear cells of a ZIKV-infected patient. |
| Application: | ELISA, FC, NT, SPR |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
Z23 was confirmed to bind ZIKV sE protein by ELISA, with an affinity of 0.44 uM shown by SPR (Wang et al, 2016). Using a FACS-based assay, it was shown that Z23 potently neutralised viral activity against infected C6/36 and Vero cells. In vivo, Z23 completely protected IFN receptor KO mice from ZIKV infection.
Short Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB00941-23.0-BT Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations