Anti-4-1BB [LOB12.3]
Catalogue Number: AB01052-23.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | CD137; TNFRSF9; 41BB; 4-1BBL Ligand; Tumor necrosis factor superfamily member 9; TNF receptor superfamily member 9; LOB 12.3; LOB123; LOB12.3 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Rabbit |
| Clone: | LOB12.3 |
| Isotype: | IgG |
| Immunogen: | This antibody was generated by immunizing rats with recombinant CD137-Fc fusion protein. |
| Application: | FC, Act |
Additional Text
Uniprot ID
P20334
Gene Name
TNFRSF9
Gene ID
21942
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody can be used to detect mouse 4-1BB (CD137). In its original rat IgG1 format, this antibody had agonistic effect and prolonged survival of mice bearing CT26 or A31 tumors. In the original publication another clone LOB12 disclosed which has a rat IgG2a isotype. This has led to some confusion in the literature with regards to the original isotype of LOB12 and LOB12.3. We offer this antibody in both formats as well as murine versions so that researchers may choose the isotype most appropriate for their assays.
Short Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB01052-23.0-BT Datasheet
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