Anti-Tim-4 [3A1]
Catalogue Number: AB01059-2.3-VXX-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 mg |
| Host name: | Mouse |
| Clone: | 3A1 |
| Isotype: | IgG2a |
| Immunogen: | This antibody was generated by immunizing a female Lewis rat with Tim-4-Ig fusion protein. |
| Application: | ELISA, FACS, FC |
Additional Text
Gene Name
TIMD4
Gene ID
276891
Uniprot ID
Q6U7R4
Antibody Clonality
Recombinant Monoclonal
Specificity
TIMD4; SMUCKLER; SMUCKLER, TIM4; Spleen, mucin-containing, knockout of lymphotoxin protein; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; TIM-4; TIMD-4
Storage Note
All VivopureX products are formulated in PBS only without addition of preservatives. To ensure optimal storage and prevent microbial contamination, only open and dispense under sterile conditions.
Application Notes
The original version of this antibody (rat IgG1) specifically bound murine Tim-4 protein, as shown in ELISA and FC assays (Rodriguez-Manzanet et al., 2008; PMID: 18354194). This antibody can block apoptotic body (AB) recognition by CD11b+ peritoneal macrophages and partially inhibit AB uptake by peritoneal B-1 cells (Rodriguez-Manzanet et al., 2010; PMID: 20368430).
Short Description
This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB01059-2.3-VXX Datasheet
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