Catalogue Number: AB01070-201.1-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Outer surface protein A |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Dog |
| Clone: | LA-2 |
| Isotype: | IgG2 |
| Immunogen: | This antibody was generated by immunising mice. |
| Application: | IF, IP, WB, NT |
Purified
P0A3N6
Recombinant Monoclonal
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
LA-2 binds to Borrelia Burgdorferi, the causative agent of Lyme disease (Borreliosis) has been used in serological analyses of B. burgdorferi isolates by immuno-blotting and immunofluorescence (Kramer et al, 1990). This antibody has also been applied to affinity purification of OspA. This antibody neutralised B. burgdorferi infectivity when passively transferred to SCID mice (Schaible et al, 1990).
This chimeric dog antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.