Anti-OspA [LA-2]

Catalogue Number: AB01070-201.1-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:Outer surface protein A
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 1 mg
Host name: Dog
Clone: LA-2
Isotype: IgG2
Immunogen: This antibody was generated by immunising mice.
Application: IF, IP, WB, NT

Additional Text

Purification

Purified

UniProt ID

P0A3N6

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

LA-2 binds to Borrelia Burgdorferi, the causative agent of Lyme disease (Borreliosis) has been used in serological analyses of B. burgdorferi isolates by immuno-blotting and immunofluorescence (Kramer et al, 1990). This antibody has also been applied to affinity purification of OspA. This antibody neutralised B. burgdorferi infectivity when passively transferred to SCID mice (Schaible et al, 1990).

Short Description

This chimeric dog antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.