Anti-influenza [2-8C]

Catalogue Number: AB01103-21.0-ABA

Manufacturer:	Vector Laboratories, Inc (ABA)
Type:	Recombinant Monoclonal
Alias:	influenza NP; influenza viral nucleoprotein; influenza nucleoprotein; NP; human influenza A virus; human influenza A viruses; Influenza A virus nucleoprotein (NP); Influenza A virus NP
Shipping Condition:	Blue Ice
Unit(s):	50 ug
Host name:	Mouse
Clone:	2-8C
Isotype:	IgM
Immunogen:	This human antibody to influenza nucleoprotein (NP) 2-8C was obtained from human subjects in compliance with good clinical practice guidelines and the Declaration of Helsinki.
Application:	ELISA, IF, WB, IHC, NT, VT

Overview
Datasheets

Additional Text

Purification

Purified

Uniprot ID

P22435

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody was used in virus titration and microneutralization assays to aid the development of pseudotyped influenza A virus as a vaccine for the induction of heterotypic immunity (Powell et al., 2012) and to demonstrate that a single cycle influenza virus coated in H7 hemagglutinin provides heterotypic protection and neutralising antibody responses to both glycoproteins (Powell et al., 2017). This antibody might be useful for Western blotting, immunofluorescence (IF) and immunocytochemistry (IHC), for instance, to better understand the differential replication properties among H9N2 avian influenza viruses of Eurasian origin (Parvin et al., 2015) and to validate that a conserved influenza A virus nucleoprotein code controls specific viral genome packaging (Moreira et al., 2016).

Short Description

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

AB01103-21.0 Datasheet

Price

£525.00

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