Catalogue Number: AB01105-10.0-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | H1N1; Influenza H1N1; Influenza A virus hemagglutinin glycoprotein; Influenza A virus HA; HA; hemagglutinin |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Human |
| Clone: | 2-12C |
| Isotype: | IgG1 |
| Immunogen: | This human 2-12C antibody was isolated from a donor that was exposed to A/California/07/2009 virus. |
| Application: | ELISA, IF, MN, Haggl-Inh, VT |
Purified
Recombinant Monoclonal
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
C3W5X2
This 2-12C antibody was isolated from a donor that was exposed to A/California/07/2009 virus. It was used as a control antibody alongside with other mAbs in enzyme-linked immunosorbent, indirect immunofluorescent, virus titration, hemagglutination inhibition (HAI), and microneutralization (MN) assays for the assessment of the binding activity of HA head-specific and head cross-reactive antibodies on cells infected with the variant viruses, and for the subsequent mapping of the HA1 K163 residue in former H1N1 viruses (Huang et al., 2015). This 2-12C antibody was reported to select a variant virus with HA substitutions K130E and G170R and, to retain the capacity to neutralize clade 6B viruses at <10 ng/ml similar to the ferret antisera (Huang et al., 2015).