Anti-influenza [2-12C]

Catalogue Number: AB01105-23.0-BT-ABA

Manufacturer:	Vector Laboratories, Inc (ABA)
Type:	Recombinant Monoclonal
Alias:	H1N1; Influenza H1N1; Influenza A virus hemagglutinin glycoprotein; Influenza A virus HA; HA; hemagglutinin
Shipping Condition:	Blue Ice
Unit(s):	1 mg
Host name:	Rabbit
Clone:	2-12C
Isotype:	IgG
Immunogen:	This human 2-12C antibody was isolated from a donor that was exposed to A/California/07/2009 virus.
Application:	ELISA, IF, MN, Haggl-Inh, VT

Overview
Datasheets

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Uniprot ID

C3W5X2

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

This 2-12C antibody was isolated from a donor that was exposed to A/California/07/2009 virus. It was used as a control antibody alongside with other mAbs in enzyme-linked immunosorbent, indirect immunofluorescent, virus titration, hemagglutination inhibition (HAI), and microneutralization (MN) assays for the assessment of the binding activity of HA head-specific and head cross-reactive antibodies on cells infected with the variant viruses, and for the subsequent mapping of the HA1 K163 residue in former H1N1 viruses (Huang et al., 2015). This 2-12C antibody was reported to select a variant virus with HA substitutions K130E and G170R and, to retain the capacity to neutralize clade 6B viruses at <10 ng/ml similar to the ferret antisera (Huang et al., 2015).

Short Description

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

AB01105-23.0-BT Datasheet

Price

£1,655.00

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