Anti-influenza [T1-3B]

Catalogue Number: AB01106-15.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:Influenza H5; Influenza NP-A; Influenza A virus hemagglutinin glycoprotein; Influenza A virus HA; HA; hemagglutinin
Shipping Condition:Blue Ice
Unit(s): 500 ug
Host name: Human
Clone: T1-3B
Isotype: IgM
Immunogen: This human antibody is a transmembrane form of IgG1 converted from those isolated from single B cells.
Application: ELISA, IF, MN, Haggl-Inh, VT

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Uniprot ID

P09345

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

In the original study, this antibody was used in conjunction with other mAbs (e.g. N2B10 mAb specific for the head of seasonal H3 HA; T2-9A mAb specific for the head of H1N1pdm09) for enzyme-linked immunosorbent, indirect immunofluorescent, virus titration, hemagglutination inhibition (HAI), and microneutralization (MN) assays to show that assessing antigenic relatedness of evolving influenza viruses with panels of defined, renewable, and human monoclonal antibodies could be a very useful an adjunct to ferret antisera in detection of antigenic drift and in the selection of viruses for inclusion in influenza vaccines (Huang et al., 2015).

Short Description

This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.