Anti-Cyclosporin A [R454511]

Catalogue Number: AB01188-23.0-BS-ABA

Manufacturer:	Vector Laboratories, Inc (ABA)
Type:	Recombinant Monoclonal
Alias:	CsA; ciclosporin A, cyclosporine A
Shipping Condition:	Blue Ice
Unit(s):	1 mg
Host name:	Rabbit
Clone:	R454511
Isotype:	IgG
Immunogen:	BALB/c mice were immunised with a D-Lys^8-Cs derivative coupled to a carrier protein.
Application:	ELISA, Crstapy

Overview
Datasheets

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

Mutagenesis of Cs-derivatives identified that R454511 binds to residues 1, 2, 3, 4, 5, 9 and 11 of CsA (Quesniaux et al, 1990). In ELISA experimenets, R454511 was found to bind to Cs conjugated with both Thr^2 (Thr^2-Cs-BSA) and Lys^8 (D-Lys^8-Cs-BSA) (Quesniaux et al, 1990). The crystal structure of R454511 in complex with CsA has been obtained to 2.65 Å resolution (Altschuh et al, 1992).

Short Description

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

AB01188-23.0-BS Datasheet

Price

£3,895.00

-

Quantity
Unit Size

Find out about delivery