Anti-Complement C3 [KF7]
Catalogue Number: AB01234-23.9-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | C3 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Rabbit |
| Clone: | KF7 |
| Isotype: | IgG |
| Immunogen: | A female New Zealand White rabbit was immunised with guinea pig C3 by three subsequent subcutaneous injections. The RNA was isolated from bone marrow, a phage display library constructed and then used to produce soluble scFv fragments. |
| Application: | ELISA, SPR |
Additional Text
Gene Name
C3
Purification
Purified
UniProt ID
P12387
Gene ID
100135462
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
ELISA was used to confirm the specificity of KF7 for guinea pig C3, with KF7 displaying high reactivity for gp C3. Reactivity with guinea pig C3a, rat C3, and human C3 was not observed. KF7 has a higher signal intensity than MF9 and MA11 (Hawlisch et al, 2000). SPR was used to quantify the dissociation rate constant of KF7; KF7 has a dissociation rate constant of 1.6x10^-4 s^-1 (Hawlisch et al, 2000).
Short Description
This chimeric rabbit antibody was made using a variable domain sequence of the original VHH format, for improved compatibility with existing reagents, assays and techniques.
AB01234-23.9 Datasheet
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