Catalogue Number: AB01237-10.9-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Marburg virus NP |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Human |
| Clone: | sdAb 4 |
| Isotype: | IgG1 |
| Immunogen: | An unbiased phage display library was generated by extracting RNA from llama blood samples. Phage-display with the MARV-Mus strain was used to select sdAb B from the phage library. |
| Application: | ELISA, Crstapy |
Purified
Recombinant Monoclonal
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
ELISA was used to establish the specificity of sdAb B for MARV virus strains (Sherwood et al, 2007). sdAb has been crystallised with its antigen NP (Garza et al, 2017). Cross-linking dimeric sdAb to NP restricted viral packaging (Darling et al, 2017).
This chimeric human antibody was made using a variable domain sequence of the original VHH format, for improved compatibility with existing reagents, assays and techniques.