Anti-Marburg virus nucleoprotein [sdAb 4]

Catalogue Number: AB01237-10.9-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:Marburg virus NP
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Human
Clone: sdAb 4
Isotype: IgG1
Immunogen: An unbiased phage display library was generated by extracting RNA from llama blood samples. Phage-display with the MARV-Mus strain was used to select sdAb B from the phage library.
Application: ELISA, Crstapy

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

ELISA was used to establish the specificity of sdAb B for MARV virus strains (Sherwood et al, 2007). sdAb has been crystallised with its antigen NP (Garza et al, 2017). Cross-linking dimeric sdAb to NP restricted viral packaging (Darling et al, 2017).

Short Description

This chimeric human antibody was made using a variable domain sequence of the original VHH format, for improved compatibility with existing reagents, assays and techniques.