Catalogue Number: AB01242-10.9-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Human |
| Clone: | VHH-12B |
| Isotype: | IgG1 |
| Immunogen: | The VHH-12B was generated by immunizing a dromedary with poliovirus type I Sabin strain, preparing cDNA libraries from lymphocytes, and then selecting for tight poliovirus binders by phage display. |
| Application: | ELISA, EM |
Purified
Recombinant Monoclonal
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
ELISA was used to show the reactivity of VHH-12B for poliovirus (Thys et al, 2010). The interaction of VHH-12B with capsid protein VP3 has been captured using cryo electron microscopy (Strauss et al, 2017).
This chimeric human antibody was made using a variable domain sequence of the original VHH format, for improved compatibility with existing reagents, assays and techniques.