Catalogue Number: AB01260-22.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Interleukin-9; IL9; Cytokine P40; T-cell growth factor P40 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Armenian Hamster |
| Clone: | D9302C12 |
| Isotype: | IgG |
| Immunogen: | This antibody was raised by immunising Armenian hamsters with Baculovirus-expressed, recombinant murine IL-9. |
| Application: | FC, Blk |
IL9
16198
P15247
Purified
Recombinant Monoclonal
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
In vitro, this antibody has inhibitory effects on IL-9 bioactivity, and inhibits the differentiation of Th17 cells and consequent production of IL-17 (Li et al, 2010). This antibody is also able to neutralise IL-9 in vivo (Li et al, 2010). Administration of this antibody suppresses acute experimental autoimmune encephalomyelitis (EAE), with an observed reduction in MOG-specific Th1 and Th17 cells in the periphery and the CNS (Li et al, 2010).