Anti-IL-9 [D9302C12]

Catalogue Number: AB01260-22.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:Interleukin-9; IL9; Cytokine P40; T-cell growth factor P40
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Armenian Hamster
Clone: D9302C12
Isotype: IgG
Immunogen: This antibody was raised by immunising Armenian hamsters with Baculovirus-expressed, recombinant murine IL-9.
Application: FC, Blk

Additional Text

Gene Name

IL9

Gene ID

16198

UniProt ID

P15247

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

In vitro, this antibody has inhibitory effects on IL-9 bioactivity, and inhibits the differentiation of Th17 cells and consequent production of IL-17 (Li et al, 2010). This antibody is also able to neutralise IL-9 in vivo (Li et al, 2010). Administration of this antibody suppresses acute experimental autoimmune encephalomyelitis (EAE), with an observed reduction in MOG-specific Th1 and Th17 cells in the periphery and the CNS (Li et al, 2010).