Anti-hINSR [IR 18-34]

Catalogue Number: AB01275-2.0-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:CD220; human insulin receptor; insulin receptor; HHF5; IR; 18 34
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Mouse
Clone: IR 18-34
Isotype: IgG2a
Immunogen: This antibody was raised by immunising BALB/c mice with purified human placental insulin receptor.
Application: IP, IHC, IB

Additional Text

Gene Name

INSR

Uniprot ID

P06213

Gene ID

3643

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody has been used in immunoprecipitation assays, with both radiolabelled human insulin receptor (hINSR) and hINSR-radiolabelled insulin complexes (Soos et al, 1986). This antibody has also been used in immunoblot analysis with purified hINSR (Soos et al, 1986) and immunohistochemistry. This antibody has been shown to have limited inhibitory effect on insulin binding to IM-9 cells (Soos et al, 1986). However, this antibody has been shown to stimulate insulin receptor autophosphorylation and kinase activity towards exogenous substrates (O'Brien et al, 1987).