Catalogue Number: AB01276-10.3-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | CD220; human insulin receptor; insulin receptor; HHF5; IR; 18 40 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Human |
| Clone: | IR 18-40 |
| Isotype: | IgG1 |
| Immunogen: | This antibody was raised by immunising BALB/c mice with purified human placental insulin receptor. |
| Application: | IP, IB |
INSR
P06213
3643
Purified
Recombinant Monoclonal
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
This antibody has been used in immunoprecipitation assays, with both radiolabelled human insulin receptor (hINSR) and hINSR-radiolabelled insulin complexes (Soos et al, 1986). This antibody has also been used in immunoblot analysis with purified hINSR (Soos et al, 1986), revealing that it reacts with the receptor's beta subunit. This antibody has been shown to have limited inhibitory effect on insulin binding to IM-9 cells (Soos et al, 1986).
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.