Anti-IGF1R [IGFR 16-13]

Catalogue Number: AB01284-3.3-ABA

Manufacturer:	Vector Laboratories, Inc (ABA)
Type:	Monoclonal Secondary Antibody - Unconjugated
Alias:	CD221; IGF1 receptor; Insulin-like growth factor 1 receptor; type I IGF receptor; Insulin-like growth factor I receptor; IGF-I receptor; 6 13
Shipping Condition:	Blue Ice
Unit(s):	200 ug
Host name:	Mouse
Clone:	IGFR 16-13
Isotype:	IgG2b
Immunogen:	This antibody was raised by immunising BALB/c mice with transfected mouse fibroblasts expressing high levels of human IGF1R (IGF1R/3T3).
Application:	IP, Stim

Overview
Datasheets

Additional Text

Gene Name

IGF1R

Gene ID

3480

Uniprot ID

P08069

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

The ability of this antibody to bind human IGF1R has been confirmed in IGF1 binding assays using both IG1FR-overexpressing IGF1R/3T3 cells and soluble receptors (Soos et al, 1992). This antibody efficiently precipitates IGF1R solubilized from IGF1R/3T3 cells and receptor-IGF1 complexes (Soos et al, 1992). When immobilised, this antibody has been shown to remove 90% of all soluble IGF1R in immunodepletion experiments (Soos et al, 1992). It has also been used to capture IGF1R N-terminal fragments as part of a ligand plate binding assay (Molina et al, 2000). This antibody strongly stimulates both IGF1 and insulin binding to IGF1R/3T3 cells, and potentiates insulin stimulation of DNA synthesis (Soos et al, 1992).

AB01284-3.3 Datasheet

Price

£390.00

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