Anti-IGF1R [IGFR 24-31]
Catalogue Number: AB01286-1.1-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Monoclonal Secondary Antibody - Unconjugated |
| Alias: | CD221; IGF1 receptor; Insulin-like growth factor 1 receptor; type I IGF receptor; Insulin-like growth factor I receptor; IGF-I receptor; 24 31 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Mouse |
| Clone: | IGFR 24-31 |
| Isotype: | IgG1 |
| Immunogen: | This antibody was raised by immunising BALB/c mice with transfected mouse fibroblasts expressing high levels of human IGF1R (IGF1R/3T3). |
| Application: | IP, IHC |
Additional Text
Gene Name
IGF1R
Gene ID
3480
Uniprot ID
P08069
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
The ability of this antibody to bind human IGF1R has been confirmed in IGF1 binding assays using both IG1FR-overexpressing IGF1R/3T3 cells and soluble receptors (Soos et al, 1992).This antibody efficiently precipitates IGF1R solubilized from IGF1R/3T3 cells and receptor-IGF1 complexes (Soos et al, 1992). When immobilised, this antibody has been shown to remove essentially all soluble IGF1R in immunodepletion experiments (Soos et al, 1992). Additionally, this antibody has been used, as part of a panel, in the immunohistochemical staining of large cell neuroendocrine carcinoma and small cell lung carcinoma (Nitadori et al, 2006) and breast carcinoma tissue microarray samples (Hartog et al, 2011).
AB01286-1.1 Datasheet
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