Anti-CD45RB [PD7/26]

Catalogue Number: AB01336-13.12-ABA

Manufacturer:	Vector Laboratories, Inc (ABA)
Type:	Recombinant Monoclonal
Alias:	Receptor-type tyrosine-protein phosphatase C; PTPRC; Leukocyte common antigen; L-CA; T200; CD45; CD45R; LY5; T200 glycoprotein; T200 leukocyte common antigen
Shipping Condition:	Blue Ice
Unit(s):	200 ug
Host name:	Human
Clone:	PD7/26
Isotype:	IgG4
Immunogen:	This antibody was raised by immunising Balb/c mice with cells from a human peripheral-blood lymphocyte line maintained in T-cell growth factor.
Application:	FACS, FC, IF, WB, IHC

Overview
Datasheets

Additional Text

Gene Name

PTPRC

Gene ID

5788

Uniprot ID

P08575

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody has been widely used in the identification of leukocytes (as CD45 is a pan-leukocyte marker) and lymphatic tumours in paraffin-embedded tissue sections. For instance, one group utilised it during the morphological characterisation of patient-derived xenografts via immunohistochemical staining of formalin-fixed, paraffin-embedded samples (Chijiwa et al., 2015). Another group used this antibody for immunofluorescence staining of similarly prepared fibroblast samples in chronic obstructive pulmonary disease (Brand et al., 2015). Finally, Deckert-Schlueter and colleagues (1998) used PD7/26 antibody when researching primary CNS lymphomas.

Short Description

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

AB01336-13.12 Datasheet

Price

£390.00

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