Anti-LRP Light Chain [8B8]

Catalogue Number: AB01381-10.0-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:low density lipoprotein receptor-related protein; LRP-85; LRP1; alpha-2-macroglobulin receptor; A2MR; APR; apolipoprotein E receptor; APOER; cluster of differentiation 91; CD91; LRP-1; 85 kDa light chain of LRP
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Human
Clone: 8B8
Isotype: IgG1
Immunogen: This antibody was raised by immunising mice with human LRP, purified by affinity chromatography from detergent placenta extracts.
Application: WB, IB

Additional Text

Gene ID

4035

Uniprot ID

Q07954

Gene Name

LRP1

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

The specificity of this antibody has been confirmed in immunoblotting experiments (Strickland et al, 1990). This antibody has been used in Western blot analysis of HEK-293 cells transfected with human full-length LRP1 fused to EGFP, to confirm fusion protein expression (Laatsch et al, 2012). Additionally, this antibody has been used in Western blot analysis to measure LRP1 protein expression levels, both in human vascular smooth muscle cells (Costales et al, 2015; Sendra et al, 2008) and human monocyte-derived macrophages (Llorente-Cortes et al, 2007).

Short Description

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.