Anti-IgG1 Fc [TP881]

Catalogue Number: AB01440-23.9-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Monoclonal Secondary Antibody - Unconjugated
Alias:immunoglobulin G1 fragment crystallizable region; immunoglobulin G1 Fc region; immunoglobulin G1
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Rabbit
Clone: TP881
Isotype: IgG
Immunogen: This antibody was raised by immunising alpacas with 1.0 mg polyclonal mouse IgG. Subsequently, the generation of nanobody immune libraries and the selection of antigen-specific nanobodies by phage display from these libraries were performed.
Application: IP, DB

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

TP881 nanobody can be used for the purification of antigens or antigen complexes previously bound to a primary antibody, as it successfully isolated mouse monoclonal IgG1 from hybridoma cell culture supernatant and then released it under physiological conditions using SUMOStar protease cleavage (Pleiner et al., 2018).

Short Description

This chimeric rabbit antibody was made using a variable domain sequence of the original VHH format, for improved compatibility with existing reagents, assays and techniques.