Anti-SIRP alpha [SAF10.1]

Catalogue Number: AB01531-1.1-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Mouse
Clone: SAF10.1
Isotype: IgG1
Immunogen: This antibody was raised by immunisisng BALB/c mice with an eukaryotically expressed SIRPα-Fc fusion protein consisting of the extracellular domain and emulsified with complete Freund's adjuvant and followed by two subsequent boosts of SIRPα-Fc fusion protein emulsified with IFA (Lee et al., 2007).
Application: FC, IF, IP, WB, BndA

Additional Text

Gene ID

140885

Gene Name

SIRPA

Uniprot ID

P78324

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Specificity

Tyrosine-protein phosphatase non-receptor type substrate 1; SHP substrate 1; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs; Bit; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Macrophage fusion receptor; MyD-1 antigen; Signal-regulatory protein alpha-1; Sirp-alpha-1; Signal-regulatory protein alpha-2; Sirp-alpha-2; Signal-regulatory protein alpha-3; Sirp-alpha-3; p84; CD172a

Application Notes

SAF10.1, can be used to detect SIRPs in a wide variety of tissues and cell types. For instance, this antibody was successfully used to detect SIRPs from COS7.2 cell lysates via Western blot (Lee et al., 2008).